to count bacteria in the intestinal tract, could be a gentle alternative to colonoscopy. Because the type and number of certain bacteria provide a clear indication of whether there is imminent danger or if Krebsentwarnung can be given. The U.S. researchers have discovered in the medical and microbiological study of 91 subjects.
Eubacterium ramulus or Ruminococcus?
Thus, the bacterium Eubacterium ramulus in the intestines of people with polyps is present in large numbers. These polyps are often a precursor to cancer tumors. The bacterium Ruminococcus, however, is to prove highly concentrated only in those with no polyps. They have a low risk of developing colon cancer. The exact determination of the composition of the individual intestinal flora could therefore be suitable as an alternative to colonoscopy, the researchers believe to Tyler Culpepper from the University of Florida.
Scientists have gefahndet in fecal samples of subjects for specific bacteria. They also collected data on dietary habits and medical history of the study participants. For the analysis of the microbiological composition of the intestinal flora, the researchers formed three equal groups: subjects with at least one polyp and an age-and gender-specific composite control group.
Alternative to colonoscopy
Three of the tiny organisms have proved to be reliable sensors for early detection: proliferation are present, the concentration of the bacterium Eubacterium is ramulus in faeces in comparison to average very high. If there are no pre-cancerous lesions to determine the bacterium Ruminococcus thrives better. And are found in tissue samples, a large number of the bacterium Acidovorax, this also indicates polyps.
"Our results suggest that developing a noninvasive test can, noting the differences in the microbiological composition of the intestinal flora and the polyps can be close to," says Tyler Culpepper. Also a special diet could control the composition of the intestinal flora. It is not clear, however, nor the reason for the varying concentrations of bacteria associated with the polyps.
The researchers present their study on the 110th Symposium of the American Society for Microbiology before, to be held today in San Diego.
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